Response: HOPE Not HYPE But Mechanisms Can Be Discussed

“Not Everything That Is Faced Can Be Changed, but Nothing Can Be Changed Until It Is Faced”: A Response to Recent Commentaries

More hype than HOPE.

More Hype Than HOPE To the Editor: In the recently published Heart Outcomes Prevention Evaluation (HOPE study),1 treatment with the ACE inhibitor ramipril was reported to reduce cardiovascular morbidity and mortality independent of blood pressure (BP) reduction. High-risk “normotensive” (BP 140/80 mm Hg) patients (n 9541) were randomized to receive either 10 mg of ramipril or placebo in additio...

Hope drives antiaging hype.

Hope drives antiaging hype EDITORIAL S THE 75 MILLION baby boomers see their parents facing age-related problems (and begin to experience some of their own), this segment of our population is spending billions of dollars in response to enticing but often misleading marketing. And because we live in a world of medical revolutions and cures, many people accept antiaging claims as fact, particular...

Pharmacogenomics: Hope or Hype?

Much has been made of the potential for personalnot altruistic companies. Incyte Inc. alone holds US ised medicine, where a genomic screen of a patient patents on more than 350 genes and has an estimated could determine which drugs will work and be free of 6,500 applications pending with 10 more applied for side effects in an individual. Much of the hope based each week [3]. They hope to make p...

Less hype, more hope.